Quick Start

This guide covers every Reply io feature:
- Aan de slag — Create account and basic setup
- How to Use Magic Sequence — Build AI-powered outreach sequences in minutes
- How to Use Templates — Save and reuse your best-performing emails
- How to Use AI Chat — Engage website visitors with AI-driven chat
- How to Use B2B Database — Find verified contacts from 1B+ records
- How to Use Triggers — Automate actions based on prospect behavior
- How to Use Multichannel Automation — Reach prospects across email, LinkedIn, SMS, and calls
- How to Use Built-in Dialer — Make calls directly from the platform
- How to Use Contact Enrichment — Fill in missing prospect data automatically
- How to Use Email Deliverability — Land in the primary inbox every time
Time needed: 5 minutes per feature
Also in this guide: Pro Tips | Common Mistakes | Probleemoplossing | Prijzen | Alternatieven
Why Trust This Guide
I’ve used Reply io for over a year and tested every feature covered here. This tutorial comes from real hands-on experience — not marketing fluff or vendor screenshots.

Reply is one of the most powerful sales engagement tools available today.
But most users only scratch the surface of what it can do.
This guide shows you how to use every major feature.
Step by step, with screenshots and pro tips.
Reply io Tutorial
This complete Reply tutorial walks you through every feature step by step, from initial setup to advanced tips that will make you a power user.

Antwoord
Automate your sales outreach across email, LinkedIn, SMS, and calls from one platform. Reply’s AI writes personalized messages and books meetings for you. Start your 14-day free trial today.
Getting Started with Reply
Before using any feature, complete this one-time setup.
It takes about 3 minutes.
Now let’s walk through each step.
Step 1: Create Your Account
Go to Reply’s website and click “Start Free Trial.”
Enter your work email and create a password.
You get a 14-day free trial with full access to core features.
✓ Checkpoint: Controleer uw inbox for a confirmation email.
Step 2: Connect Your Email Account
Click “Settings” then “Email Accounts” in the left sidebar.
Choose Gmail, Outlook, or custom SMTP to connect your mailbox.
Follow the on-screen prompts to authorize access.
Here’s what the dashboard looks like:

✓ Checkpoint: You should see your connected email in the accounts list.
Step 3: Complete Initial Setup
Set your daily sending limits to protect your sender reputation.
Enable email warm-up for each connected mailbox.
Import your first contact list via CSV or CRM synchroniseren.
✅ Done: You’re ready to use any feature below.
How to Use Reply io Magic Sequence
Magische reeks lets you create AI-powered outreach sequences in minutes.
Here’s how to use it step by step.
Watch Magic Sequence in action:

Now let’s break down each step.
Step 1: Open the Sequence Builder
Click “Sequences” in the left menu, then “New Sequence.”
Select “Start with Jason AI” to use the Magic Sequence feature.
Step 2: Describe Your Target Audience
Enter your ideal customer profile and what you’re selling.
Jason AI will generate a full multichannel sequence for you.
Review the suggested emails, LinkedIn steps, and follow-ups.
✓ Checkpoint: You should see a complete sequence with multiple steps.
Step 3: Customize and Launch
Edit any message to match your brand stem.
Set the delay between each step and hit “Start.”
✅ Result: Your AI-built sequence is now running and sending personalized outreach.
💡 Pro-tip: Let Jason AI handle your first sequence. Then duplicate and tweak it for different audiences to save time.
How to Use Reply io Templates
Sjablonen lets you save and reuse your best-performing email copy.
Here’s how to use it step by step.
Watch Templates in action:

Now let’s break down each step.
Step 1: Navigate to Templates
Click “Templates” in the left sidebar menu.
You’ll see pre-built templates and a button to create new ones.
Step 2: Create or Choose a Template
Click “New Template” and write your subject line and body.
Use variables like {{first_name}} and {{company}} to personalize.
✓ Checkpoint: You should see your variables highlighted in the editor.
Step 3: Save and Use in Sequences
Save the template with a clear name for easy access later.
Insert it into any sequence step with one click.
✅ Result: Your template is saved and ready to drop into any future campaign.
💡 Pro-tip: Keep emails under 80 words with a single call to action. Short emails get higher reply rates.
How to Use Reply io AI Chat
AI-chat lets you capture and qualify website visitors with an AI chatbot.
Here’s how to use it step by step.
Watch AI Chat in action:

Now let’s break down each step.
Step 1: Access the AI Chat Section
Click “AI Chat” in the left navigation menu.
Select “Create New Chatbot” to get started.
Step 2: Train Your Chatbot
Upload your product information or paste your website URL.
The AI learns your bedrijf and answers visitor questions automatically.
✓ Checkpoint: You should see the chatbot preview with sample responses.
Step 3: Install on Your Website
Copy the embed code and paste it into your website’s header.
The chatbot will appear on your site and start capturing leads.
✅ Result: Your AI chatbot is live and qualifying visitors around the clock.
💡 Pro-tip: Connect AI Chat to your CRM so captured leads flow directly into your sales pipeline.
How to Use Reply io B2B Database
B2B-database lets you find verified contacts from over 1 billion records.
Here’s how to use it step by step.
Watch B2B Database in action:

Now let’s break down each step.
Step 1: Open Reply Data
Click “Data” in the left sidebar to open the B2B database.
You’ll see search filters for industry, company size, and job title.
Step 2: Apply Filters to Find Leads
Set your target criteria like job title, location, and company size.
The database returns matching contacts with verified email addresses.
✓ Checkpoint: You should see a list of prospects matching your filters.
Step 3: Add Contacts to a Sequence
Select the contacts you want and click “Add to Sequence.”
Choose an existing sequence or create a new one for these leads.
✅ Result: Your new leads are added to an outreach sequence and will receive messages automatically.
💡 Pro-tip: Use the “Recently Funded” or “Job Change” filters to find prospects who are most likely to buy right now.
How to Use Reply io Triggers
Triggers lets you automate actions based on what your prospects do.
Here’s how to use it step by step.
Watch Triggers in action:

Now let’s break down each step.
Step 1: Go to the Triggers Section
Click “Sequences” and then select the “Triggers” tab.
You’ll see options for event-based and time-based triggers.
Step 2: Set Your Trigger Conditions
Choose a trigger event like “Email Opened” or “Link Clicked.”
Then set the action, such as “Move to Another Sequence” or “Notify Team.”
✓ Checkpoint: You should see the trigger rule displayed in your automatisering stroom.
Step 3: Activate the Trigger
Toggle the trigger to “Active” and save your settings.
Reply io will now act on that event whenever it happens.
✅ Result: Your outreach now responds to prospect behavior automatically.
💡 Pro-tip: Set a trigger to move hot leads to a faster follow-up sequence when they click a pricing link.
How to Use Reply io Multichannel Automation
Multichannel Automation lets you reach prospects across email, LinkedIn, SMS, and phone.
Here’s how to use it step by step.
Watch Multichannel Automation in action:

Now let’s break down each step.
Step 1: Create a Multichannel Sequence
Click “Sequences” then “New Sequence” and select “Multichannel.”
You’ll see options to add email, LinkedIn, call, and SMS steps.
Step 2: Add Steps for Each Channel
Drag and drop channel steps in your preferred order.
Write your message for each step and set delays between them.
✓ Checkpoint: You should see a visual flow with all your channel steps connected.
Step 3: Launch Your Campaign
Add your contact list and click “Start” to begin outreach.
Reply io sends messages across all channels on autopilot.
✅ Result: Your prospects receive coordinated messages across email, LinkedIn, SMS, and phone.
💡 Pro-tip: Start with email, follow up on LinkedIn 2 days later, then add a call step. This sequence gets the highest response rates.
How to Use Reply io Built-in Dialer
Built-in Dialer lets you make phone calls directly from Reply io.
Here’s how to use it step by step.
Watch Built-in Dialer in action:

Now let’s break down each step.
Step 1: Enable the Dialer
Go to “Settings” and select “Calls” to set up your phone number.
Choose a local or toll-free number for your outbound calls.
Step 2: Make Your First Call
Open a contact’s profile and click the phone icon to dial.
The call connects through your browser — no extra software needed.
✓ Checkpoint: You should hear the call ringing in your browser.
Step 3: Log Call Notes
After the call, add notes and set the call outcome.
Reply io saves the call recording and syncs notes to your CRM.
✅ Result: Your call is logged with notes, and the recording is saved for review.
💡 Pro-tip: Add a call step after your second email in a sequence. Prospects who opened your email are warm and more likely to answer.
How to Use Reply io Contact Enrichment
Contact Enrichment lets you fill in missing prospect data automatically.
Here’s how to use it step by step.
Watch Contact Enrichment in action:

Now let’s break down each step.
Step 1: Select Contacts to Enrich
Go to your contact list and select the contacts with missing data.
Click “Enrich” from the action menu at the top.
Step 2: Choose Enrichment Fields
Select which fields you want to fill — email, phone, job title, or company.
Reply io searches its database to find the missing information.
✓ Checkpoint: You should see the enrichment progress bar filling up.
Step 3: Review Enriched Data
Check the updated contact records to verify the new data.
Remove any contacts where enrichment didn’t find valid information.
✅ Result: Your contact list now has complete, verified data for better outreach.
💡 Pro-tip: Enrich contacts before adding them to a sequence. Verified emails reduce bounce rates and protect your sender reputation.
How to Use Reply io Email Deliverability
E-mailbezorgbaarheid lets you land in the primary inbox and avoid spam folders.
Here’s how to use it step by step.
Watch Email Deliverability in action:

Now let’s break down each step.
Step 1: Run the Email Health Check
Go to “Deliverability” in the left menu and click “Email Health Check.”
The tool scans your domain setup for SPF, DKIM, and DMARC records.
Step 2: Enable Email Warm-Up
Toggle on warm-up for each connected email account.
Reply io gradually increases your sending volume to build reputation.
✓ Checkpoint: You should see the warm-up status set to “Active” for your mailboxes.
Step 3: Monitor Your Deliverability Score
Check the deliverability dashboard daily for the first two weeks.
Watch your inbox placement rate climb as warm-up progresses.
✅ Result: Your emails are now landing in the primary inbox with a strong sender reputation.
💡 Pro-tip: Run warm-up for at least 2 weeks before launching your first campaign. This gives your domain the best chance of high inbox placement.
Reply io Pro Tips and Shortcuts
After testing Reply io for over a year, here are my best tips.
Toetsenbord sneltoetsen
| Action | Shortcut |
|---|---|
| Open new sequence | Ctrl + N |
| Send test email | Ctrl + T |
| Search contacts | Ctrl + K |
| Toggle sidebar | Ctrl + B |
Hidden Features Most People Miss
- AI Variables: Use dynamic variables to insert recent company news or job role changes into opening lines automatically.
- Conditional Steps: Set “if/then” logic in sequences so LinkedIn steps only fire if email wasn’t opened.
- Google Postmaster Integration: Connect Google Postmaster to track your domain reputation directly inside Reply io.
Reply io Common Mistakes to Avoid
Mistake #1: Skipping Email Warm-Up
❌ Wrong: Sending 500 emails on day one from a brand-new mailbox.
✅ Right: Enable warm-up for 2 weeks before launching any campaign.
Mistake #2: Writing Long Emails
❌ Wrong: Sending 300-word emails with multiple links and CTAs.
✅ Right: Keep emails under 80 words with one clear call to action.
Mistake #3: Not Using A/B Testing
❌ Wrong: Running the same subject line for every prospect without testing.
✅ Right: A/B test subject lines and email body copy on every sequence to find what works.
Reply io Troubleshooting
Problem: Emails Landing in Spam
Cause: Your domain lacks proper SPF, DKIM, or DMARC records, or warm-up wasn’t completed.
Repareren: Run the Email Health Check under Deliverability settings. Fix any flagged DNS records and enable warm-up for at least 14 days.
Problem: LinkedIn Automation Not Working
Cause: Your LinkedIn account isn’t connected, or you’ve hit LinkedIn’s daily connection limit.
Repareren: Reconnect your LinkedIn account in Settings. Keep daily connection requests under 25 to avoid restrictions.
Problem: Low Open Rates
Cause: Poor subject lines, bad sender reputation, or emails going to spam.
Repareren: A/B test subject lines. Check your deliverability score. Use personalization variables in the subject line.
📌 Opmerking: If none of these fix your issue, contact Reply io support via in-app chat.
Wat is Reply IO?
Antwoord io is a sales engagement tool that automates outreach across email, LinkedIn, SMS, and phone.
Think of it like having an AI sales assistant that finds leads, writes personalized messages, and books meetings for you.
Watch this quick overview:
It includes these key features:
- Magic Sequence: AI-generated outreach sequences built in minutes
- Sjablonen: Save and reuse your best-performing email copy
- AI Chat: Capture and qualify website visitors with an AI chatbot
- B2B Database: Access 1B+ verified contacts for lead sourcing
- Triggers: Automate actions based on prospect behavior
- Multichannel Automation: Coordinate outreach across email, LinkedIn, SMS, and calls
- Built-in Dialer: Make and log calls without leaving the platform
- Contactverrijking: Fill in missing prospect data from 1B+ records
- Email Deliverability: Warm-up, health checks, and anti-spam tools
For a full review, see our Reply io review.

Reply io Pricing
Here’s what Reply io costs in 2026:
| Plan | Prijs | Het beste voor |
|---|---|---|
| E-mailvolume | $49 per gebruiker per maand | Teams focused on high-volume email outreach |
| Multikanaals | $89 per gebruiker per maand | Sales teams needing email, LinkedIn, SMS, and calls |
| Jason AI SDR | $300 per gebruiker per maand | Teams wanting fully automated AI-driven outreach |
Gratis proefperiode: Yes — 14-day free trial with access to all core features. No credit card required.
Geld-terug-garantie: No standard refund policy. Review terms before subscribing.

💰 Best Value: Multichannel at $89/user/month — it includes email, LinkedIn, SMS, and calls in one plan.
Reply io vs Alternatives
How does Reply io compare? Here’s the competitive landscape:
| Hulpmiddel | Het beste voor | Prijs | Rating |
|---|---|---|---|
| Antwoord io | Multichannel sales automation | $49/maand | ⭐ 4.2 |
| Meteen | High-volume koude e-mail | $30/mo | ⭐ 4.3 |
| Snov | Email finding + outreach | $29.25/mo | ⭐ 4.5 |
| Jager | Email verification + outreach | $0/maand | ⭐ 4.5 |
| UpLead | B2B contact database | $0/maand | ⭐ 4.2 |
| Mailshake | Simple cold email campaigns | $25/mo | ⭐ 4.0 |
| Lemlist | Personalized cold outreach | $55/mo | ⭐ 4.5 |
| Specht | B2B cold email for agencies | $20/maand | ⭐ 4.5 |
Quick picks:
- Best overall: Reply io — Most complete multichannel platform with AI features
- Best budget: Woodpecker — Starts at $20/month with solid cold email tools
- Best for beginners: Mailshake — Simple interface with no learning curve
- Best for high-volume email: Instantly — Built for sending thousands of cold emails daily
🎯 Reply io Alternatives
Looking for Reply io alternatives? Here are the top options:
- 🚀 Meteen: Sends high-volume cold emails with unlimited mailbox connections and built-in warm-up tools.
- 💰 Snov.io: Combines email finding, verification, and drip campaigns in one affordable platform.
- 🔧 Hunter.io: Finds and verifies professional email addresses with a generous free plan included.
- 📊 UpLead: Provides 95% accurate B2B contact data with real-time email verification built in.
- 👶 Mailshake: Makes cold email simple for beginners with an easy drag-and-drop sequence bouwer.
- 🎨 Lemlijst: Creates personalized cold emails with custom images and dynamic landing pages per prospect.
- 🏢 Specht: Designed for B2B agencies running cold email campaigns for multiple clients at once.
- ⚡ Smartlead: Rotates unlimited mailboxes automatically for high-volume sending with strong deliverability.
- 🔥 Verkoopmedewerker: Scales cold email outreach with automated follow-ups and detailed tracking analytics.
- 🧠 Klenty: Adds AI-powered cadences with deep CRM integration for enterprise sales teams.
- 🔒 Warmbox: Warms up email accounts to protect sender reputation and boost inbox placement rates.
- 💼 Maildoso: Manages dozens of mailboxes at once for agencies scaling cold email across clients.
- 🌟 Manyreach: Offers a credit-based model that’s perfect for freelancers and small outreach teams.
- ⭐ Warm: Focuses on email warm-up and deliverability for both B2B and B2C senders.
For the full list, see our Reply io alternatieven guide.
⚔️ Reply io Compared
Here’s how Reply io stacks up against each competitor:
- Reply io vs Instantly: Instantly wins for pure email volume. Reply io wins for multichannel outreach across email, LinkedIn, and calls.
- Reply io vs Snov.io: Snov.io is cheaper for email finding. Reply io offers more channels and AI-powered sequence building.
- Reply io vs Hunter.io: Hunter.io is best for email lookup. Reply io is the better choice for full outreach automation.
- Reply io versus UpLead: UpLead excels at B2B data accuracy. Reply io adds outreach automation on top of its built-in database.
- Reply io vs Mailshake: Mailshake is simpler and cheaper. Reply io has more channels, AI features, and a larger contact database.
- Reply io vs Lemlist: Lemlist is stronger for email personalization. Reply io offers broader multichannel automation.
- Reply io vs Woodpecker: Woodpecker is better for small agencies on a budget. Reply io suits teams needing AI and multichannel.
- Reply io versus Smartlead: Smartlead is better for unlimited mailbox rotation. Reply io offers more channels beyond email.
- Reply io vs Saleshandy: Saleshandy is more affordable for email-only outreach. Reply io adds LinkedIn, calls, and AI features.
- Reply io vs Klenty: Klenty has deeper CRM integration. Reply io has a larger B2B database and more AI-tools.
- Reply io versus Warmbox: Warmbox is a warm-up-only tool. Reply io includes warm-up plus full outreach automation.
- Reply io vs Maildoso: Maildoso is built for managing bulk mailboxes. Reply io is better for full sales engagement workflows.
- Reply io vs Manyreach: Manyreach is cheaper for small teams. Reply io offers more features and enterprise-grade automation.
- Reply io vs Warmy: Warmy focuses only on deliverability. Reply io is a complete outreach platform with deliverability built in.
Start Using Reply Now
You learned how to use every major Reply io feature:
- ✅ Magic Sequence
- ✅ Templates
- ✅ AI Chat
- ✅ B2B Database
- ✅ Triggers
- ✅ Multichannel Automation
- ✅ Built-in Dialer
- ✅ Contact Enrichment
- ✅ Email Deliverability
Next step: Pick one feature and try it now.
Most people start with Magic Sequence.
It takes less than 5 minutes.
Veelgestelde vragen
What is Reply io used for?
Reply io is a sales engagement platform that automates outreach across email, LinkedIn, SMS, and phone calls. Sales teams use it to find leads, send personalized messages at scale, and book meetings without manual work. It’s built for B2B sales teams, agencies, and solo founders running outbound campaigns.
Is Reply io free?
Reply io offers a 14-day free trial with access to all core features. No credit card is required to start. After the trial ends, paid plans start at $49 per user per month for the Email Volume plan.
How much does Reply io cost?
Reply io has three main plans. The Email Volume plan costs $49 per user per month. The Multichannel plan runs $89 per user per month. The Jason AI SDR plan is $300 per user per month for fully automated AI outreach. All prices are billed annually.
Can Reply AI write emails for me?
Yes. Reply io’s Jason AI can generate complete email sequences based on your target audience and product description. It writes personalized subject lines, email body copy, and follow-up messages. You can edit any AI-generated content before sending.
Is Reply io good for beginners?
Reply io has a learning curve, but the Magic Sequence feature makes it beginner-friendly. You describe your audience and Jason AI builds the sequence for you. The 14-day free trial gives you time to learn the platform before paying. Start with email-only sequences before adding other channels.













